Natural selection in the evolution of SARS-CoV-2 in bats created a generalist virus and highly capable human pathogen박쥐에서 SARS-CoV-2의 진화에서 자연 선택은 일반 바이러스와 고도로 유능한 인간 병원체를 만들었습니다Research Article Published on 2021-03-122022-08-13 Journal: PLoS Biology [Category] Biology and Life Sciences, Fulltext, SARS, 유전자 메커니즘, 조류인플루엔자, 치료기술, [키워드] accompanied acting acute respiratory syndrome coronavirus adaptive Analysis ancestor Anti-viral Antiviral base bat bat Sarbecovirus bats can not Cell Coinfection coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 CpG CpG composition detect early phase Evidence evidence of Evolution Evolution of SARS-CoV-2 horseshoe bats Host hosts Human human pathogen humans include involved Lineage lineages mechanism moderate natural natural selection nucleotide nucleotides pandemic positive Positive selection progenitor recombinant Recombination required respiratory reveal RmYN02 Sarbecoviruses SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Support the cells the early SARS-CoV-2 Transmission virus viruses while [DOI] 10.1371/journal.pbio.3001115 PMC 바로가기 [Article Type] Research Article
Intra-genome variability in the dinucleotide composition of SARS-CoV-2Rapid Communication Published on 2020-07-132022-10-28 Journal: Virus Evolution [Category] COVID-19, [키워드] absence approach artificial conservation coronavirus CpG CpG composition CpG dinucleotides Cross-species transmission dinucleotide E gene envelope exhibit Frame Frequency Genome Host humans Hypothesis Modification motif much higher not differ observation ORF ORF10 other coronavirus Region replication site SARS-CoV-2 SARS-CoV-2 replication SARS-CoV-2 vaccine Single-stranded RNA viruses suppress the Coronaviridae the SARS-CoV-2 genome tissue tropism Vaccine Variability Variation virus Virus evolution [DOI] 10.1093/ve/veaa057 PMC 바로가기 [Article Type] Rapid Communication